daptomycin

Term ID

CHEBI:600103

Synonyms

• Cidecin
• Cubicin
• daptomicina
• daptomycin
• daptomycine
• daptomycinum
• LY 146032
• N-decanoyl-L-tryptophyl-L-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-seryl-threo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine 1.13-3.4-lactone
• N-decanoyl-L-tryptophyl-L-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-seryl-threo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine epsilon(1)-lactone
• N-decanoyl-L-tryptophyl-L-asparaginyl-N-[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-ox

Definition

A polypeptide comprising N-decanoyltryptophan, asparagine, aspartic acid, threonine, glycine, ornithine, aspartic acid, D-alanine, aspartic acid, glycine, D-serine, threo-3-methylglutamic acid and 3-anthraniloylalanine (also known as kynurinine) coupled in sequence and lactonised by condensation of the carboxylic acid group of the 3-anthraniloylalanine with the alcohol group of the threonine residue.

References

• cas:103060-53-3
• drugbank:DB00080
• kegg.compound:C12013
• kegg.drug:D01080
• pubmed:14622998
• pubmed:15227539
• pubmed:15271343
• pubmed:15500379
• pubmed:15815985
• pubmed:15870461
• pubmed:16311632
• pubmed:17402833
• pubmed:18360590
• pubmed:18989686
• pubmed:19015332
• pubmed:19303806
• pubmed:19875242
• pubmed:20522545
• wikipedia.en:Daptomycin

Ontology

ChEBI  ( EBI )

Resources

CTD