docetaxel trihydrate

Term ID

CHEBI:59809

Synonyms

• 4-(acetyloxy)-13alpha-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7beta,10beta-trihydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate--water (1/3)
• docetaxel
• N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel trihydrate
• N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol trihydrate

Definition

The trihydrate form of docetaxel. It is used for the treatment of breast, ovarian, and non-small cell lung cancer, and with prednisone or prednisolone in hormone-refractory metastatic prostate cancer.

References

• Beilstein:10054412
• CAS:148408-66-6
• DrugBank:DB01248
• KEGG:D02165
• Patent:EP253738
• Patent:US4814470

Ontology

ChEBI  ( EBI )