diflorasone

Term ID

CHEBI:59750

Synonyms

(6alpha,11beta,16beta)-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
6alpha,9-difluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
diflorasona
diflorasone
diflorasonum

Definition

The 16beta-analogue of flumethasone. It is used as the 17,21-diacetate as a topical anti-inflammatory and antipruritic in the treatment of various skin disorders.

References

Beilstein:5645455
CAS:2557-49-5
DrugBank:DB00223
KEGG:D07827
Patent:GB881334
Patent:GB898293
Patent:GB912015
Patent:US3557158
Wikipedia:Diflorasone

Ontology

ChEBI ( EBI )

Relationships

is a type of: 3-oxo-Delta(1),Delta(4)-steroid 11beta-hydroxy steroid 17alpha-hydroxy steroid 20-oxo steroid 21-hydroxy steroid ... Show All 9 Terms

3-oxo-Delta(1),Delta(4)-steroid 11beta-hydroxy steroid 17alpha-hydroxy steroid 20-oxo steroid 21-hydroxy steroid fluorinated steroid glucocorticoid primary alpha-hydroxy ketone tertiary alpha-hydroxy ketone Show first 5 Terms
has_parent_hydride: pregnane

pregnane Show first 5 Terms
has_role: anti-inflammatory drug

anti-inflammatory drug Show first 5 Terms
inverse has_functional_parent: diflorasone diacetate

diflorasone diacetate Show first 5 Terms

Phenotype

Phenotype resulting from diflorasone

Phenotype where environments contain diflorasone

Phenotype modified by environments containing diflorasone

Human Disease Model