clocortolone

Term ID

CHEBI:59582

Synonyms

• 9-chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methyl-1,4-pregnadien-3,20-dione
• 9-chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
• 9-chloro-6alpha-fluoro-16alpha-methyl-1,4-pregnadiene-11beta,21-diol-3,20-dione
• clocortolona
• clocortolone
• clocortolonum

Definition

16α-Methylpregna-1,4-diene-3,20-dione bearing hydroxy substituents at the 11β and 21 positions, fluorine at position 6 and chlorine at position 9. A medium potency corticosteroid, it is used as its 21-O-pivalate or caproate ester for the relief of inflammatory and pruritic (itching) skin disorders.

References

• beilstein:6318064
• cas:4828-27-7
• drugbank:DB00838
• kegg.drug:D07719
• patent:DE2011559
• patent:NL6412708
• patent:US3729495
• wikipedia.en:Clocortolone

Ontology

ChEBI  ( EBI )

Resources

CTD