cefditoren

Term ID

CHEBI:59343

Synonyms

• (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(Z)-2-(4-methyl-1,3-thiazol-5-yl)ethenyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 7beta-(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido-3-[(Z)-2-(4-methyl-1,3-thiazol-5-yl)ethenyl]-3,4-didehydrocepham-4-carboxylic acid
• cefditoren

Definition

A broad spectrum, third-generation cephalosporin antibiotic with (Z)-2-(4-methyl-1,3-thiazol-5-yl)ethenyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. Generally administered as its orally absorbed pivaloyloxymethyl ester prodrug, it is used for the treatment of mild to moderate infections caused by susceptible strains of microorganisms in acute bacterial exacerbation of chronic bronchitis, community-acquired pneumonia, pharyngitis/tonsillitis, and uncomplicated skin and skin-structure infections.

References

• Beilstein:8174297
• CAS:104145-95-1
• DrugBank:DB01066
• KEGG:D07639
• PMID:11687308
• PMID:11856949
• PMID:22521692
• PMID:22675264
• PMID:23009290
• PMID:25871785
• PMID:29017833
• PMID:29199418
• Patent:EP475610
• Patent:US2003225265
• Patent:US4839650
• Reaxys:8174297

Ontology

ChEBI  ( EBI )

Resources

CTD