Search Ontology:
ChEBI

polymyxin

Term ID
CHEBI:59062
Synonyms
  • polymixin
  • polymycin
  • polymyxins
Definition
Polymyxins are antibiotics with a general structure consisting of a cyclic peptide with a long hydrophobic tail. They disrupt the structure of the bacterial cell membrane by interacting with its phospholipids. Polymyxins are produced by the Gram-positive bacterium Bacillus polymyxa and are selectively toxic for Gram-negative bacteria.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has subtype
has_role
Phenotype
Phenotype resulting from polymyxin
Phenotype where environments contain polymyxin
Phenotype modified by environments containing polymyxin
Human Disease Model