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ChEBI

ifosfamide

Term ID
CHEBI:5864
Synonyms
  • 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
  • ifosfamida
  • ifosfamide
  • ifosfamidum
  • Iphosphamide
  • Isofosfamide
  • Isophosphamide
  • isosfamide
  • N,3-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
Definition
The simplest member of the class of ifosfamides that is 1,3,2-oxazaphosphinan-2-amine 2-oxide substituted by 2-chloroethyl groups on both the nitrogen atoms respectively. It is a nitrogen mustard alkylating agent used in the treatment of advanced breast cancer.
References
  • beilstein:611835
  • cas:3778-73-2
  • drugbank:DB01181
  • drugcentral:1421
  • hmdb:HMDB0015312
  • kegg.compound:C07047
  • kegg.drug:D00343
  • lincs.smallmolecule:LSM-5118
  • pubmed:11550152
  • pubmed:11669554
  • reaxys:5802893
  • wikipedia.en:Ifosfamide
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from ifosfamide
Phenotype where environments contain ifosfamide
Phenotype modified by environments containing ifosfamide
Phenotype affecting ifosfamide
Human Disease Model