Search Ontology:
ChEBI

myriocin

Term ID
CHEBI:582124
Synonyms
  • (2S,3R,4R)-(E)-2-amino-3,4-dihydroxy-2-hydroxymethyl-14-oxoeicos-6-enoic acid
  • (2S,3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid
  • (2S,3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid
  • antibiotic ISP-1
  • antibiotic ISP-I
  • ISP-1
  • ISP-I
  • thermozymocidin
Definition
An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from myriocin
Phenotype where environments contain myriocin
Phenotype modified by environments containing myriocin
Human Disease Model
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