Search Ontology:
ChEBI

hydrochlorothiazide

Term ID
CHEBI:5778
Synonyms
  • 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
  • Esidrix (TN)
  • hidroclorotiazida
  • hydrochlorothiazide
  • hydrochlorothiazidum
Definition
A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
References
  • cas:58-93-5
  • drugbank:DB00999
  • drugcentral:1385
  • hmdb:HMDB0001928
  • kegg.compound:C07041
  • kegg.drug:D00340
  • lincs.smallmolecule:LSM-5308
  • pdb-ccd:HCZ
  • pubmed:24055851
  • pubmed:24657333
  • pubmed:24849193
  • reaxys:625101
  • wikipedia.en:Hydrochlorothiazide
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from hydrochlorothiazide
Phenotype where environments contain hydrochlorothiazide
Phenotype modified by environments containing hydrochlorothiazide
Phenotype affecting hydrochlorothiazide
Human Disease Model