radicicol

Term ID

CHEBI:556075

Synonyms

• (1aR,2Z,4E,14R,15aR)-8-chloro-9,11-dihydroxy-14-methyl-1a,14,15,15a-tetrahydro-6H-oxireno[e][2]benzoxacyclotetradecine-6,12(7H)-dione
• Monorden
• RADICICOL

Definition

An antifungal macrolactone antibiotic, obtained from Diheterospora chlamydosporia and Chaetomium chiversii that inhibits protein tyrosine kinase and heat shock protein 90 (Hsp90).

References

• cas:12772-57-5
• drugbank:DB03758
• pdb-ccd:RDC
• pubmed:16232632
• pubmed:16920739
• pubmed:18667483
• pubmed:20093793
• pubmed:20961859
• pubmed:21800052
• reaxys:15865423
• wikipedia.en:Radicicol

Ontology

ChEBI  ( EBI )

Resources

CTD