Search Ontology:
ChEBI

guanadrel

Term ID
CHEBI:5555
Synonyms
  • 1-(1,4-dioxaspiro[4.5]dec-2-ylmethyl)guanidine
  • Guanadrel
  • guanadrelum
Definition
A spiroketal resulting from the formal condensation of the keto group of cyclohexanone with the hydroxy groups of 1-(2,3-dihydroxypropyl)guanidine. A postganglionic adrenergic blocking agent formerly used (generally as the sulfate salt) for the management of hypertension, it has been largely superseded by other drugs less likely to cause orthostatic hypotension (dizzy spells on standing up or stretching).
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
inverse is_conjugate_acid_of
is_conjugate_base_of
Phenotype
Phenotype resulting from guanadrel
Phenotype where environments contain guanadrel
Phenotype modified by environments containing guanadrel
Human Disease / Model Data
Citations
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