cytochalasin D

Term ID

CHEBI:529996

Synonyms

• (3S,3aR,4S,6S,7E,10S,12R,13E,15R,15aR)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate
• 7,18-Dihydroxy-10-phenyl-5,16,18-trimethyl-(11)cytochalas-21-acetoxy-6(12),13,19-trien-17-one
• Cytohalasin D
• Lygosporin A
• Zygosporin A

Definition

An organic heterotricyclic compound that is a mycotoxin produced by Helminthosporium and other moulds which is cell permeable and a potent inhibitor of actin polymerisation and DNA synthesis.

References

• cas:22144-77-0
• pdb-ccd:CY9
• pubmed:20010439
• pubmed:22305779
• pubmed:22684244
• pubmed:22728040
• pubmed:23615686
• pubmed:5800426
• pubmed:7199049
• reaxys:1632828
• wikipedia.en:Cytochalasin_D

Ontology

ChEBI  ( EBI )

Resources

CTD