cytochalasin D

Term ID

CHEBI:529996

Synonyms

(3S,3aR,4S,6S,7E,10S,12R,13E,15R,15aR)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate
7,18-Dihydroxy-10-phenyl-5,16,18-trimethyl-(11)cytochalas-21-acetoxy-6(12),13,19-trien-17-one
Cytohalasin D
Lygosporin A
Zygosporin A

Definition

An organic heterotricyclic compound that is a mycotoxin produced by Helminthosporium and other moulds which is cell permeable and a potent inhibitor of actin polymerisation and DNA synthesis.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: acetate ester alkaloid cyclic ketone cytochalasin gamma-lactam ... Show All 9 Terms

acetate ester alkaloid cyclic ketone cytochalasin gamma-lactam organic heterotricyclic compound secondary alcohol tertiary alcohol tertiary alpha-hydroxy ketone Show first 5 Terms
has_role: actin polymerisation inhibitor antineoplastic agent DNA synthesis inhibitor mycotoxin

actin polymerisation inhibitor antineoplastic agent DNA synthesis inhibitor mycotoxin Show first 5 Terms

Phenotype

Phenotype resulting from cytochalasin D

Phenotype where environments contain cytochalasin D

Phenotype modified by environments containing cytochalasin D

Human Disease Model