gatifloxacin

Term ID

CHEBI:5280

Synonyms

• 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
• 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid
• 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• AM 1155
• gatifloxacin
• gatifloxacine
• gatifloxacino
• gatifloxacinum

Definition

A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.

References

• CAS:112811-59-3
• DrugBank:DB01044
• Drug_Central:1280
• Gmelin:2281206
• KEGG:C07661
• KEGG:D08011
• LINCS:LSM-5139
• PMID:10737746
• PMID:12190308
• PMID:12620077
• PMID:12873512
• PMID:12904069
• PMID:15125930
• PMID:15745831
• PMID:15911273
• PMID:16078842
• PMID:16337791
• PMID:16554151
• PMID:16759086
• PMID:17043111
• PMID:17043131
• PMID:17064062
• PMID:17116666
• PMID:17116668
• PMID:17157008
• PMID:17220425
• PMID:17261623
• PMID:17276057
• PMID:17296740
• PMID:17325221
• PMID:17387152
• PMID:17804222
• PMID:17933535
• PMID:17960928
• PMID:18078756
• PMID:18304818
• PMID:26963935
• PMID:7473575
• Patent:EP230295
• Patent:US4980470
• Reaxys:7445861
• Wikipedia:Gatifloxacin

Ontology

ChEBI  ( EBI )

Resources

CTD