gatifloxacin

Term ID

CHEBI:5280

Synonyms

1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid
1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
AM 1155
gatifloxacin
gatifloxacine
gatifloxacino
gatifloxacinum

Definition

A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.

References

cas:112811-59-3
drugbank:DB01044
drugcentral:1280
gmelin:2281206
kegg.compound:C07661
kegg.drug:D08011
lincs.smallmolecule:LSM-5139
patent:EP230295
patent:US4980470
pubmed:10737746
pubmed:12190308
pubmed:12620077
pubmed:12873512
pubmed:12904069
pubmed:15125930
pubmed:15745831
pubmed:15911273
pubmed:16078842
pubmed:16337791
pubmed:16554151
pubmed:16759086
pubmed:17043111
pubmed:17043131
pubmed:17064062
pubmed:17116666
pubmed:17116668
pubmed:17157008
pubmed:17220425
pubmed:17261623
pubmed:17276057
pubmed:17296740
pubmed:17325221
pubmed:17387152
pubmed:17804222
pubmed:17933535
pubmed:17960928
pubmed:18078756
pubmed:18304818
pubmed:26963935
pubmed:7473575
reaxys:7445861
wikipedia.en:Gatifloxacin

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from gatifloxacin

Phenotype where environments contain gatifloxacin

Phenotype modified by environments containing gatifloxacin

Phenotype affecting gatifloxacin

Human Disease Model