Search Ontology:
ChEBI
hycanthone
- Term ID
- CHEBI:52768
- Synonyms
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- 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9-one
- 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one
- 1-(2-diethylaminoethylamino)-4-(hydroxymethyl)thioxanthen-9-one
- 1-{[2-(diethylamino)ethyl]amino}-4-(hydroxymethyl)-9H-thioxanthen-9-one
- hicantona
- Hycanthon
- hycanthone
- hycanthonum
- Lucanthone metabolite
- Definition
- A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.
- References
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- Beilstein:1402722
- CAS:3105-97-3
- Drug_Central:1383
- KEGG:D00541
- LINCS:LSM-5614
- PMID:1888160
- PMID:21935361
- PMID:2957147
- PMID:5573958
- PMID:626982
- PMID:7369442
- Patent:NL6410359
- Patent:US3294803
- Patent:US3312598
- Reaxys:1402722
- Wikipedia:Hycanthone
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
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- has_functional_parent
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- has_role
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- inverse is_conjugate_acid_of
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- is_conjugate_base_of
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Show first 5 Terms
Phenotype
Phenotype resulting from hycanthone
Phenotype where environments contain hycanthone
Phenotype modified by environments containing hycanthone
Human Disease / Model Data
Citations