Search Ontology:
ChEBI
PP121
- Term ID
- CHEBI:50915
- Synonyms
-
- 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- PP-121
- Definition
- A pyrazolopyrimidine that is 1H-pyrazolo[3,4-d]pyrimidine which is substituted by a cyclopentyl, 1H-pyrrolo[2,3-b]pyridin-5-yl, and amino groups at positions 1, 3 and 4, respectively. It is a dual inhibitor of tyrosine and phosphoinositide kinases and exhibits anti-cancer properties.
- References
-
- cas:1092788-83-4
- drugbank:DB08052
- pdb-ccd:KS1
- pubmed:18849971
- pubmed:23596204
- pubmed:24867098
- pubmed:26056008
- pubmed:26235881
- pubmed:26514495
- pubmed:27135311
- pubmed:27886301
- pubmed:31562255
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from PP121
Phenotype where environments contain PP121
Phenotype modified by environments containing PP121
Phenotype affecting PP121
Human Disease Model