Search Ontology:
ChEBI

calcipotriol

Term ID
CHEBI:50749
Synonyms
  • (1S,3R,5Z,7E,22E,24S)-26,27-cyclo-9,10-secocholesta-5,7,10,22-tetraene-1,3,24-triol
  • Calcipotriene
  • calcipotriol
  • Daivonex
  • Dovonex
  • MC 903
  • MC-903
  • MC903
Definition
A seco-cholestane that is 26,27-cyclo-9,10-secocholesta-5,7,10,22-tetraene carrying additional hydroxy substituents at positions 1, 3 and 24. It is used (as its hydrate) in combination with betamethasone dipropionate, a corticosteroid, for the topical treatment of plaque psoriasis in adult patients.
References
  • cas:112965-21-6
  • drugbank:DB02300
  • drugcentral:465
  • hmdb:HMDB0015567
  • kegg.drug:D01125
  • lipidmaps:LMST03020106
  • patent:US4866048
  • patent:WO8700834
  • pdb-ccd:MC9
  • pubmed:23441902
  • pubmed:23621170
  • pubmed:24090798
  • pubmed:24286371
  • pubmed:24419155
  • pubmed:24533503
  • pubmed:24592364
  • pubmed:24593129
  • pubmed:24670691
  • pubmed:24788893
  • pubmed:24907534
  • pubmed:25027750
  • pubmed:25355140
  • pubmed:25484388
  • pubmed:25561873
  • pubmed:25574190
  • pubmed:25592908
  • pubmed:25904071
  • pubmed:26081515
  • pubmed:26224733
  • pubmed:37731472
  • pubmed:38854231
  • pubmed:39214171
  • pubmed:7994616
  • reaxys:5309193
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from calcipotriol
Phenotype where environments contain calcipotriol
Phenotype modified by environments containing calcipotriol
Phenotype affecting calcipotriol
Human Disease Model