milrinone

Term ID

CHEBI:50693

Synonyms

• 1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrile
• 2-methyl-6-oxo-1,6-dihydro-3,4'-bipyridine-5-carbonitrile
• milrinona
• Milrinone
• milrinonum

Definition

A member of the class of bipyridines that is 2-pyridone which is substituted at positions 3, 5, and 6 by cyano, pyrid-4-yl, and methyl groups, respectively. It is used (particularly intravenously, as the lactate) for the short-term management of severe heart failure.

References

• beilstein:3546821
• cas:78415-72-2
• drugbank:DB00235
• drugcentral:1809
• hmdb:HMDB0014380
• kegg.compound:C07224
• kegg.drug:D00417
• lincs.smallmolecule:LSM-3493
• patent:BE886336
• patent:US4313951
• patent:US4413127
• pdb-ccd:MIL
• pubmed:10634314
• pubmed:14624413
• pubmed:14638547
• pubmed:21905056
• pubmed:21971319
• reaxys:3546821
• wikipedia.en:Milrinone

Ontology

ChEBI  ( EBI )