podophyllotoxin

Term ID

CHEBI:50305

Synonyms

(-)-podophyllotoxin
(5R,5aR,8aR,9R)-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one
9-HYDROXY-5-(3,4,5-TRIMETHOXYPHENYL)-5,8,8A,9-TETRAHYDROFURO[3',4':6,7]NAPHTHO[2,3-D][1,3]DIOXOL-6(5AH)-ONE
Condylox
Podofilox
Podophyllinic acid lactone
Podophyllotoxin
Podophyllotoxin 7
PPT

Definition

An organic heterotetracyclic compound that has a furonaphthodioxole skeleton bearing a 3,4,5-trimethoxyphenyl substituent. It is found in the roots and rhizomes of Podophyllum species and is used for the topical treatment of genital warts.

References

CAS:518-28-5
DrugBank:DB01179
Drug_Central:3481
HMDB:HMDB0031452
KEGG:C10874
KEGG:D05529
KNApSAcK:C00000610
LINCS:LSM-3055
PDBeChem:POD
PMID:15803102
PMID:22621772
PMID:23161544
PMID:23798883
PMID:8112825
Reaxys:99163
Wikipedia:Podophyllotoxin

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: furonaphthodioxole lignan organic heterotetracyclic compound

furonaphthodioxole lignan organic heterotetracyclic compound Show first 5 Terms
has_role: antimitotic antineoplastic agent keratolytic drug microtubule-destabilising agent plant metabolite ... Show All 6 Terms

antimitotic antineoplastic agent keratolytic drug microtubule-destabilising agent plant metabolite tubulin modulator Show first 5 Terms
inverse has_functional_parent: etoposide teniposide

etoposide teniposide Show first 5 Terms

Phenotype

Phenotype resulting from podophyllotoxin

Phenotype where environments contain podophyllotoxin

Phenotype modified by environments containing podophyllotoxin

Human Disease / Model Data

Citations