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ChEBI

pizotifen

Term ID
CHEBI:50212
Synonyms
  • 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine
  • pizotifen
  • pizotifene
  • pizotifeno
  • pizotifenum
  • Pizotyline
Definition
A benzocycloheptathiophene that is 9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene 4-ylidene)-1-methylpiperidine which is joined from the 4 position to the 4 position of an N-methylpiperidine moiety by a double bond. It is a sedating antihistamine, with strong serotonin antagonist and weak antimuscarinic activity. It is generally used as the malate salt for the treatment of migraine and the prevention of headache attacks during cluster periods.
References
  • CAS:15574-96-6
  • Drug_Central:2220
  • KEGG:D05523
  • LINCS:LSM-3695
  • Patent:BE636717
  • Patent:US3272826
  • Reaxys:753534
  • Wikipedia:Pizotifen
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_functional_parent
has_role
inverse is_conjugate_acid_of
is_conjugate_base_of
Phenotype
Phenotype resulting from pizotifen
Phenotype where environments contain pizotifen
Phenotype modified by environments containing pizotifen
Human Disease Model