Search Ontology:
ChEBI

vandetanib

Term ID
CHEBI:49960
Synonyms
  • 4-BROMO-2-FLUORO-N-[(4E)-6-METHOXY-7-[(1-METHYLPIPERIDIN-4-YL)METHOXY]QUINAZOLIN-4(1H)-YLIDENE]ANILINE
  • N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
  • vandetanib
  • Zactima
  • ZD 6474
  • ZD6474
Definition
A quinazoline that is 7-[(1-methylpiperidin-4-yl)methoxy]quinazoline bearing additional methoxy and 4-bromo-2-fluorophenylamino substituents at positions 6 and 4 respectively. Used for the treatment of symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
inverse has_functional_parent
Phenotype
Phenotype resulting from vandetanib
Phenotype where environments contain vandetanib
Phenotype modified by environments containing vandetanib
Human Disease / Model Data
Citations