5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole

Term ID

CHEBI:49852

Synonyms

1-beta-D-ribofuranosyl-5,6-dichlorobenzimidazole
5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole
5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole
5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole
5,6-dichlorobenzimidazole 1-beta-D-ribofuranoside
5,6-dichlorobenzimidazole riboside
5,6-dichlororibofuranosylbenzimidazole
dichlororibofuranosylbenzimidazole
DRB

Definition

A 1-ribosylbenzimidazole that is 5,6-dichloro-1H-benzimidazole attached to a β-D-ribofuranosyl residue at position 1 via a glycosidic (N-glycosyl) linkage. It is an inhibitor for RNA polymerase II transcription.

References

cas:53-85-0
drugbank:DB08473
hmdb:HMDB0242505
pdb-ccd:RFZ
pubmed:16727940
pubmed:21074544
pubmed:2461242
pubmed:2464694
pubmed:2803263
pubmed:2835431
pubmed:2914905
pubmed:2930526
pubmed:30219263
pubmed:32031322
pubmed:34361059
pubmed:3477544
pubmed:35732126
pubmed:37537243
pubmed:6180307
pubmed:6191332
pubmed:6501318
pubmed:664245
pubmed:6953414
pubmed:7592583
pubmed:8185933
pubmed:8355707
pubmed:8647904
reaxys:39123
wikipedia.en:5,6-Dichloro-1-%CE%B2-D-ribofuranosylbenzimidazole

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from 5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole

Phenotype where environments contain 5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole

Phenotype modified by environments containing 5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole

Phenotype affecting 5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole

Human Disease Model