etodolac

Term ID

CHEBI:4909

Synonyms

• (+-)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
• (1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid
• (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid
• 1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid
• 1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
• 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid
• ETODOLAC
• etodolaco
• etodolacum
• ETODOLIC ACID

Definition

A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.

References

• cas:41340-25-4
• drugbank:DB00749
• drugcentral:1103
• hmdb:HMDB0014887
• kegg.drug:D00315
• lincs.smallmolecule:LSM-1781
• patent:DE2301525
• patent:US3939178
• pubmed:15369391
• pubmed:2527995
• pubmed:28166217
• pubmed:2970548
• wikipedia.en:Etodolac

Ontology

ChEBI  ( EBI )

Resources

CTD