ezetimibe

Term ID

CHEBI:49040

Synonyms

• (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one
• Ezedoc
• ezetimiba
• ezetimibe
• ezetimibum
• Ezetrol
• Zetia

Definition

A β-lactam that is azetidin-2-one which is substituted at 1, 3, and 4 by p-fluorophenyl, 3-(p-fluorophenyl)-3-hydroxypropyl, and 4-hydroxyphenyl groups, respectively (the 3R,3'S,4S enantiomer).

References

• cas:163222-33-1
• drugbank:DB00973
• drugcentral:1125
• hmdb:HMDB0015108
• kegg.drug:D01966
• lincs.smallmolecule:LSM-5536
• pubmed:17587760
• pubmed:18585981
• pubmed:23219178
• pubmed:23266293
• pubmed:23317398
• pubmed:23471229
• pubmed:23510093
• pubmed:23538020
• reaxys:7981967
• wikipedia.en:Ezetimibe

Ontology

ChEBI  ( EBI )