deferasirox

Term ID

CHEBI:49005

Synonyms

4-[3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid
deferasirox
deferasiroxum
Exjade
ICL 670
ICL 670A

Definition

A member of the class of triazoles, deferasirox is 1,2,4-triazole substituted by a 4-carboxyphenyl group at position 1 and by 2-hydroxyphenyl groups at positions 3 and 5. An orally active iron chelator, it is used to manage chronic iron overload in patients receiving long-term blood transfusions.

References

Beilstein:8442898
CAS:201530-41-8
DrugBank:DB01609
Drug_Central:3128
KEGG:D03669
Reaxys:8442898

Ontology

ChEBI ( EBI )

Relationships

is a type of: benzoic acids monocarboxylic acid phenols triazoles

benzoic acids monocarboxylic acid phenols triazoles Show first 5 Terms
has_functional_parent: 2,2'-(1-phenyl-1H-1,2,4-triazole-3,5-diyl)diphenol

2,2'-(1-phenyl-1H-1,2,4-triazole-3,5-diyl)diphenol Show first 5 Terms
has_role: iron chelator

iron chelator Show first 5 Terms

Phenotype

Phenotype resulting from deferasirox

Phenotype where environments contain deferasirox

Phenotype modified by environments containing deferasirox

Human Disease / Model Data

Citations