ethosuximide

Term ID

CHEBI:4887

Synonyms

• (+-)-2-ethyl-2-methylsuccinimide
• 2-ethyl-2-methylsuccinimide
• 2-methyl-2-ethylsuccinimide
• 3-ethyl-3-methyl-2,5-pyrrolidinedione
• 3-ethyl-3-methylpyrrolidine-2,5-dione
• 3-ethyl-3-methylsuccinimide
• 3-methyl-3-ethylpyrrolidine-2,5-dione
• 3-methyl-3-ethylsuccinimide
• Aethosuximide
• alpha-ethyl-alpha-methylsuccinimide
• alpha-methyl-alpha-ethylsuccinimide
• ethosuximide
• ethosuximidum
• etosuximida
• gamma-ethyl-gamma-methyl-succinimide
• gamma-methyl-gamma-ethyl-succinimide

Definition

A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.

References

• CAS:77-67-8
• Chemspider:3175
• DrugBank:DB00593
• Drug_Central:1087
• HMDB:HMDB0014731
• KEGG:C07505
• KEGG:D00539
• LINCS:LSM-5195
• PMID:12873507
• PMID:16606760
• PMID:1681105
• PMID:17011080
• PMID:17046248
• PMID:17451232
• PMID:17481896
• PMID:1847429
• PMID:18949032
• PMID:19005061
• PMID:1992141
• PMID:2061925
• PMID:21332949
• PMID:21945797
• PMID:2296016
• PMID:2308142
• PMID:3336019
• PMID:3820228
• PMID:8246220
• PMID:8627613
• PMID:8691481
• PMID:9016327
• Reaxys:117054
• Wikipedia:Ethosuximide

Ontology

ChEBI  ( EBI )

Resources

CTD