ergothioneine

Term ID

CHEBI:4828

Synonyms

(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylammonio)propanoate
(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate
(alphaS)-alpha-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-1H-imidazole-4-ethanaminium inner salt
(S)-(1-carboxy-2-(2-mercaptoimidazol-4-yl)ethyl)trimethylammonium hydroxide
2-mercaptohistidine trimethylbetaine
3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)-2-trimethylammonio-propanoate
ergothionine
erythrothioneine
L-ergothioneine
L-thioneine
sympectothion
thiolhistidine-betaine
thiolhistidinebetaine

Definition

A L-histidine derivative that is N^α,N^α,N^α-trimethyl-L-histidine in which the hydrogen at position 2 on the imdazole ring is replaced by a mercapto group. A naturally occurring metabolite of histidine synthesized by bacteria and fungi with antioxidant properties. It is found ubiquitously in plants and animals and is present in many human foodstuffs.

References

cas:497-30-3
hmdb:HMDB0003045
kegg.compound:C05570
metacyc.compound:CPD-15276
pubmed:15030958
pubmed:15744438
pubmed:17616140
pubmed:18670092
pubmed:18841979
pubmed:19660151
pubmed:19911007
pubmed:20420449
pubmed:23418129
pubmed:23494799
pubmed:23922985
pubmed:24392160
pubmed:25154712
pubmed:25736892
pubmed:26079795
pubmed:26149121
pubmed:26229105
pubmed:26338495
pubmed:26412552
pubmed:26542137
pubmed:26579093
pubmed:26634964
pubmed:26713511
pubmed:26772879
pubmed:26774486
pubmed:26921894
pubmed:26994919
pubmed:27101740
pubmed:27134772
pubmed:27306320
pubmed:27444382
pubmed:7144630
reaxys:5755696
reaxys:8411606
wikipedia.en:Ergothioneine

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from ergothioneine

Phenotype where environments contain ergothioneine

Phenotype modified by environments containing ergothioneine

Phenotype affecting ergothioneine

Human Disease Model