ergothioneine

Term ID

CHEBI:4828

Synonyms

(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylammonio)propanoate
(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate
(alphaS)-alpha-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-1H-imidazole-4-ethanaminium inner salt
(S)-(1-carboxy-2-(2-mercaptoimidazol-4-yl)ethyl)trimethylammonium hydroxide
2-mercaptohistidine trimethylbetaine
3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)-2-trimethylammonio-propanoate
ergothioneine thiol
ergothionine
erythrothioneine
L-ergothioneine
L-thioneine
sympectothion
thiolhistidine-betaine
thiolhistidinebetaine

Definition

A L-histidine derivative that is N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine in which the hydrogen at position 2 on the imdazole ring is replaced by a mercapto group. A naturally occurring metabolite of histidine synthesized by bacteria and fungi with antioxidant properties. It is found ubiquitously in plants and animals and is present in many human foodstuffs.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: amino-acid betaine L-histidine derivative sulfur-containing amino acid

amino-acid betaine L-histidine derivative sulfur-containing amino acid Show first 5 Terms
has_role: antioxidant chelator fungal metabolite plant metabolite xenobiotic metabolite

antioxidant chelator fungal metabolite plant metabolite xenobiotic metabolite Show first 5 Terms
inverse has_functional_parent: 2-sulfenohercynine S-methyl-L-ergothioneine

2-sulfenohercynine S-methyl-L-ergothioneine Show first 5 Terms
inverse is_conjugate_acid_of: ergothioneine(1+)

ergothioneine(1+) Show first 5 Terms
inverse is_tautomer_of: ergothioneine thione form

ergothioneine thione form Show first 5 Terms
is_conjugate_base_of: ergothioneine(1+)

ergothioneine(1+) Show first 5 Terms
is_tautomer_of: ergothioneine thione form

ergothioneine thione form Show first 5 Terms

Phenotype

Phenotype resulting from ergothioneine

Phenotype where environments contain ergothioneine

Phenotype modified by environments containing ergothioneine

Human Disease Model