emetine

Term ID

CHEBI:4781

Synonyms

• 6',7',10,11-tetramethoxyemetan
• cephaeline methyl ether
• cephaline-O-methyl ether
• Emetan
• Emetin
• Emetine
• methyl cephaeline

Definition

A pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties.

References

• beilstein:6253162
• cas:483-18-1
• drugbank:DB13393
• drugcentral:1001
• kegg.compound:C09421
• knapsack:C00001849
• lincs.smallmolecule:LSM-2041
• metacyc.compound:CPD-14817
• pubmed:14119536
• pubmed:16109351
• pubmed:17094176
• pubmed:19227966
• pubmed:29872540
• pubmed:31436297
• pubmed:31533472
• pubmed:31734270
• pubmed:31775307
• pubmed:31964796
• pubmed:32245264
• pubmed:32251767
• reaxys:100834
• wikipedia.en:Emetine

Ontology

ChEBI  ( EBI )

Resources

CTD