emedastine

Term ID

CHEBI:4779

Synonyms

• 1-(2-Ethoxy-ethyl)-2-(4-methyl-[1,4]diazepan-1-yl)-1H-benzoimidazole
• 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole
• 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzimidazole
• 1-[2-(ethoxy)ethyl]-2-(4-methyl-1-homopiperazinyl)benzimidazole
• emedastina
• EMEDASTINE
• emedastinum

Definition

1-Methyl-1,4-diazepane in which the hydrogen attached to the nitrogen at position 4 is substituted by a 1-(2-ethoxyethyl)-1H-benzimidazol-2-yl group. A relatively selective histamine H1 antagonist, it is used as the difumatate salt for allergic rhinitis, urticaria, and pruritic skin disorders, and in eyedrops for the symptomatic relief of allergic conjuntivitis.

References

• Beilstein:6068161
• CAS:87233-61-2
• DrugBank:DB01084
• Drug_Central:999
• KEGG:C07785
• KEGG:D07890
• LINCS:LSM-5331
• Patent:US4430343
• Wikipedia:Emedastine

Ontology

ChEBI  ( EBI )

Resources

CTD