Search Ontology:
ChEBI

roflumilast

Term ID
CHEBI:47657
Synonyms
  • 3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
  • Daliresp
  • roflumilast
  • roflumilastum
Definition
A benzamide obtained by formal condensation of the carboxy group of 3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzoic acid with the amino group of 3,5-dichloropyridin-4-amine. Used for treatment of bronchial asthma and chronic obstructive pulmonary disease.
References
  • cas:162401-32-3
  • drugcentral:3531
  • kegg.drug:D05744
  • patent:US2008181876
  • patent:US2008221111
  • patent:WO2008017827
  • patent:WO2008090355
  • pdb-ccd:ROF
  • pubmed:21778965
  • pubmed:21913898
  • pubmed:21965226
  • pubmed:22041526
  • pubmed:22258322
  • pubmed:22284994
  • pubmed:22306235
  • pubmed:22364166
  • pubmed:22385203
  • pubmed:22421519
  • pubmed:22425388
  • pubmed:22433610
  • pubmed:22452977
  • pubmed:22500119
  • pubmed:22605906
  • pubmed:22723325
  • pubmed:22790061
  • pubmed:22791991
  • pubmed:22833385
  • pubmed:22952743
  • pubmed:22955248
  • pubmed:22997924
  • reaxys:9802592
  • wikipedia.en:Roflumilast
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from roflumilast
Phenotype where environments contain roflumilast
Phenotype modified by environments containing roflumilast
Phenotype affecting roflumilast
Human Disease Model