loracarbef

Term ID

CHEBI:47544

Synonyms

• (6R,7S)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 7beta-[(2R)-2-amino-2-phenylacetyl]nitrilo-3-chloro-3,4-didehydrocepham-4-carboxylic acid
• LORACABEF
• loracarbef
• loracarbefum

Definition

A synthetic "carba" analogue of cefaclor, with carbon replacing sulfur at position 1. Used to treat a wide range of infections caused by both gram-positive and gram-negative bacteria.

References

• cas:76470-66-1
• drugbank:DB00447
• drugcentral:1603
• hmdb:HMDB0014590
• kegg.drug:D08143
• lincs.smallmolecule:LSM-5429
• patent:EP14476
• patent:US4708956
• pdb-ccd:LOR
• pubmed:1553350
• pubmed:1621740
• pubmed:1621742
• pubmed:29017833
• pubmed:8453172
• pubmed:9131470
• reaxys:3631282

Ontology

ChEBI  ( EBI )