Search Ontology:
ChEBI
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide
- Term ID
- CHEBI:47495
- Synonyms
-
- H 89
- H-89
- H89
- N-(2-{[3-(4-bromophenyl)prop-2-en-1-yl]amino}ethyl)isoquinoline-5-sulfonamide
- N-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide
- N-[2-[[3-(4-bromophenyl)-2-propen-1-yl]amino]ethyl]-5-isoquinolinesulfonamide
- protein kinase inhibitor H89
- Definition
- A member of the class of isoquinolines that is the sulfonamide obtained by formal condensation of the sulfo group of isoquinoline-5-sulfonic acid with the primary amino group of N1-[3-(4-bromophenyl)prop-2-en-1-yl]ethane-1,2-diamine. It is a protein kinase A inhibitor.
- References
-
- cas:127243-85-0
- chemspider:3420
- drugbank:DB07995
- lincs.smallmolecule:LSM-2608
- pubmed:19461967
- pubmed:26596264
- pubmed:26747511
- pubmed:26750148
- pubmed:26807018
- pubmed:26939705
- pubmed:28267871
- pubmed:32031573
- pubmed:33352792
- pubmed:33450772
- pubmed:33820812
- pubmed:33964190
- reaxys:8160271
- wikipedia.en:H-89
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
Phenotype
Phenotype resulting from N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide
Phenotype where environments contain N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide
Phenotype modified by environments containing N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide
Phenotype affecting N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide
Human Disease Model