Search Ontology:
ChEBI
E3040
- Term ID
- CHEBI:4732
- Synonyms
-
- 5,7-dimethyl-2-(methylamino)-4-(pyridin-3-ylmethyl)-1,3-benzothiazol-6-ol
- 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole
- E-3040
- E3040
- Definition
- A member of the class of benzothiazoles that is 1,3-benzothiazole substituted by a methylnitrilo group, (pyridin-3-yl)methyl group, methyl group, hydroxy group and methyl group at position 2,4,5,6 and 7, respectively. It is a dual inhibitor of 5-lipoxygenase and thromboxane A2 synthetase and exhibits anti-inflammatory properties. The drug was being developed by Eisai (Tokyo, Japan) for the treatment of bowel disease.
- References
-
- cas:145096-30-6
- kegg.compound:C11593
- pubmed:10206322
- pubmed:10594872
- pubmed:11011031
- pubmed:11430933
- pubmed:11557269
- pubmed:12023941
- pubmed:15319327
- pubmed:15598971
- pubmed:7562509
- pubmed:8536337
- pubmed:8592681
- pubmed:9023311
- pubmed:9262353
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
Phenotype
Phenotype resulting from E3040
Phenotype where environments contain E3040
Phenotype modified by environments containing E3040
Phenotype affecting E3040
Human Disease Model