doxazosin

Term ID

CHEBI:4708

Synonyms

• 1-(4-Amino-6,7-dimethoxy-2-chinazolinyl)-4-(2,3-dihydro-1,4-benzodioxixin-2-ylcarbonyl)piperazin
• 1-(4-Amino-6,7-Dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin
• 2-[4-(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine
• Doxazosin
• doxazosina
• doxazosine
• doxazosinum

Definition

A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.

References

• Beilstein:731849
• CAS:74191-85-8
• DrugBank:DB00590
• Drug_Central:954
• HMDB:HMDB0014728
• KEGG:C06970
• KEGG:D07874
• LINCS:LSM-4335
• PMID:17171413
• PMID:18559700
• Patent:DE2847623
• Patent:US4188390
• Reaxys:731849
• Wikipedia:Doxazosin

Ontology

ChEBI  ( EBI )

Resources

CTD