disulfiram

Term ID

CHEBI:4659

Synonyms

1,1',1'',1'''-[disulfanediylbis(carbonothioylnitrilo)]tetraethane
1,1'-dithiobis(N,N-diethylthioformamide)
Antabuse
bis(diethylthiocarbamoyl) disulfide
Disulfiram
N,N,N',N'-tetraethylthiuram disulfide
tetraethylthioperoxydicarbonic diamide
Tetraethylthiuram disulfide
tetraethylthiuram disulphide

Definition

An organic disulfide that results from the formal oxidative dimerisation of N,N-diethyldithiocarbamic acid. A multi-enzyme inhibitor that is used in alcohol aversion therapy and also exhibits anticancer properties.

References

cas:97-77-8
drugbank:DB00822
drugcentral:928
hmdb:HMDB0014960
kegg.compound:C01692
kegg.drug:D00131
lincs.smallmolecule:LSM-5467
metacyc.compound:DISULFIRAM
pesticides:disulfiram
pubmed:10841824
pubmed:11005259
pubmed:11716515
pubmed:14978246
pubmed:15325261
pubmed:15709459
pubmed:16426571
pubmed:16661923
pubmed:16666414
pubmed:16880974
pubmed:17079463
pubmed:17579916
pubmed:17667894
pubmed:18579431
pubmed:19720750
pubmed:19782464
pubmed:19787200
pubmed:21471244
pubmed:24496638
pubmed:25133664
pubmed:25445071
pubmed:25464072
pubmed:25476326
pubmed:25495604
pubmed:25557293
pubmed:25565438
pubmed:25657800
pubmed:25777347
pubmed:26033731
pubmed:26224731
pubmed:26235918
pubmed:26239994
pubmed:26314552
pubmed:26517513
pubmed:26550292
pubmed:31151194
pubmed:32963852
pubmed:32971817
pubmed:33731397
pubmed:34012274
pubmed:34045896
pubmed:8442800
pubmed:8572926
reaxys:1712560
wikipedia.en:Disulfiram

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from disulfiram

Phenotype where environments contain disulfiram

Phenotype modified by environments containing disulfiram

Phenotype affecting disulfiram

Human Disease Model