zardaverine

Term ID

CHEBI:46548

Synonyms

• 6-(4-(Difluoromethoxy)-3-methoxyphenyl)-3(2H)-pyridazinone
• 6-(4-DIFLUOROMETHOXY-3-METHOXY-PHENYL)-2H-PYRIDAZIN-3-ONE
• 6-[4-(difluoromethoxy)-3-methoxyphenyl]pyridazin-3(2H)-one
• zardaverina
• zardaverine
• zardaverinum

Definition

A pyridazinone derivative in which pyridazin-3(2H)-one is substituted at C-6 with a 4-(difluoromethoxy)-3-methoxyphenyl group. It is a phosphodiesterase inhibitor, selective for PDE3 and 4.

References

• cas:101975-10-4
• lincs.smallmolecule:LSM-2833
• pdb-ccd:ZAR
• pubmed:12387865
• pubmed:12952271
• pubmed:1426207
• pubmed:1648920
• pubmed:1665311
• pubmed:1700309
• pubmed:1723951
• pubmed:1787170
• pubmed:7644776
• pubmed:7684572
• pubmed:7925141
• pubmed:8035322
• pubmed:8369979
• pubmed:8381357
• pubmed:8392340

Ontology

ChEBI  ( EBI )

Resources

CTD