dipivefrin

Term ID

CHEBI:4646

Synonyms

(+-)-4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate
1-(3',4'-dipivaloyloxyphenyl)-2-methylamino-1-ethanol
4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate
4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diyl bis(2,2-dimethylpropanoate)
dipivalyl epinephrine
Dipivefrin
dipivefrina
dipivefrine
dipivefrinum

Definition

The dipivalate ester of (+-)-epinephrine (racepinephrine). A pro-drug of epinephrine, the hydrochloride is used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension.

References

Beilstein:2165183
CAS:52365-63-6
DrugBank:DB00449
Drug_Central:922
KEGG:C06963
KEGG:D02349
LINCS:LSM-1583
Patent:DE2152058
Patent:DE2343657
Patent:US3809714
Patent:US4085270
Wikipedia:Dipivefrin

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: ethanolamines pivalate ester

ethanolamines pivalate ester Show first 5 Terms
has_functional_parent: adrenaline

adrenaline Show first 5 Terms
has_role: adrenergic agonist antiglaucoma drug ophthalmology drug prodrug sympathomimetic agent

adrenergic agonist antiglaucoma drug ophthalmology drug prodrug sympathomimetic agent Show first 5 Terms
inverse is_conjugate_acid_of: dipivefrin(1+)

dipivefrin(1+) Show first 5 Terms
is_conjugate_base_of: dipivefrin(1+)

dipivefrin(1+) Show first 5 Terms

Phenotype

Phenotype resulting from dipivefrin

Phenotype where environments contain dipivefrin

Phenotype modified by environments containing dipivefrin

Human Disease Model