fluconazole

Term ID

CHEBI:46081

Synonyms

2,4-difluoro-alpha,alpha-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol
2-(2,4-difluorophenyl)-1,3-bis-(1H-1,2,4-triazol-1-yl)propan-2-ol
2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL
Biozole
Diflucan
Elazor
fluconazol
fluconazole
fluconazolum
Triflucan

Definition

A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

References

Beilstein:4269710
CAS:86386-73-4
DrugBank:DB00196
Drug_Central:1187
HMDB:HMDB0014342
KEGG:D00322
LINCS:LSM-2106
PDBeChem:TPF
PMID:11366931
PMID:16822276
PMID:23171950
PMID:23793863
Patent:GB2099818
Patent:US4404216
Reaxys:7311650
Wikipedia:Fluconazole

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: conazole antifungal drug difluorobenzene tertiary alcohol triazole antifungal drug

conazole antifungal drug difluorobenzene tertiary alcohol triazole antifungal drug Show first 5 Terms
has_functional_parent: 1,3-difluorobenzene

1,3-difluorobenzene Show first 5 Terms
has_parent_hydride: 1H-1,2,4-triazole

1H-1,2,4-triazole Show first 5 Terms
has_role: environmental contaminant P450 inhibitor xenobiotic

environmental contaminant P450 inhibitor xenobiotic Show first 5 Terms
inverse has_functional_parent: Fosfluconazole

Fosfluconazole Show first 5 Terms

Phenotype

Phenotype resulting from fluconazole

Phenotype where environments contain fluconazole

Phenotype modified by environments containing fluconazole

Human Disease Model