trimethoprim

Term ID

CHEBI:45924

Synonyms

• 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine
• 5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine
• 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine
• Proloprim
• Trimethoprim
• Trimpex

Definition

An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.

References

• beilstein:625127
• cas:738-70-5
• drugbank:DB00440
• drugcentral:2755
• gmelin:808843
• hmdb:HMDB0014583
• kegg.compound:C01965
• kegg.drug:D00145
• lincs.smallmolecule:LSM-5246
• pdb-ccd:TOP
• pubmed:10423629
• pubmed:10969053
• pubmed:11051625
• pubmed:14629008
• pubmed:15203044
• pubmed:16311012
• pubmed:18816075
• pubmed:25111783
• pubmed:25361939
• pubmed:26546758
• pubmed:26566149
• pubmed:26942256
• pubmed:26987772
• pubmed:28166217
• pubmed:7602118
• pubmed:8911701
• reaxys:625127
• vsdb:1745
• wikipedia.en:Trimethoprim

Ontology

ChEBI  ( EBI )

Resources

CTD