Search Ontology:
ChEBI

paclitaxel

Term ID
CHEBI:45863
Synonyms
  • (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha R*,betaS*),11alpha,12alpha,12balpha))-beta-(Benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramet
  • 4alpha,10beta-bis(acetyloxy)-13alpha-[(2S,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyloxy]-1,7beta-dihydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate
  • 5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine
  • paclitaxel
  • TAXOL
  • Taxol A
Definition
A tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. Note that the use of the former generic name 'taxol' is now limited, as Taxol is a registered trade mark.
References
  • CAS:33069-62-4
  • DrugBank:DB01229
  • Drug_Central:2044
  • KEGG:C07394
  • KEGG:D00491
  • KNApSAcK:C00002365
  • PDBeChem:TA1
  • Wikipedia:Paclitaxel
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
inverse has_functional_parent
Phenotype
Phenotype resulting from paclitaxel
Phenotype where environments contain paclitaxel
Phenotype modified by environments containing paclitaxel
Human Disease Model