Search Ontology:
ChEBI
(4R)-4-methyl-L-glutamate(1-)
- Term ID
- CHEBI:45753
- Synonyms
-
- (2S,4R)-2-amino-4-carboxypentanoate
- (2S,4R)-4-methylglutamate
- (2S,4R)-4-methylglutamate(1-)
- 2S,4R-4-methylglutamate
- Definition
- An α-amino-acid anion that is the conjugate base of (4R)-4-methyl-L-glutamic acid resulting from the deprotonation of the α-carboxy group. It is a potent agonist of the kainate receptors GluK1 and GluK2.
- References
-
- drugbank:DB03425
- patent:US2002115688
- pdb-ccd:SYM
- pubmed:10336078
- pubmed:10478637
- pubmed:11389172
- pubmed:11730722
- pubmed:14994336
- pubmed:15721240
- pubmed:17590480
- pubmed:17622578
- pubmed:19074430
- pubmed:27580033
- pubmed:31311973
- pubmed:9145919
- pubmed:9517418
- pubmed:9835217
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from (4R)-4-methyl-L-glutamate(1-)
Phenotype where environments contain (4R)-4-methyl-L-glutamate(1-)
Phenotype modified by environments containing (4R)-4-methyl-L-glutamate(1-)
Phenotype affecting (4R)-4-methyl-L-glutamate(1-)
Human Disease Model