dihydroergotamine

Term ID

CHEBI:4562

Synonyms

(10alphaH)-5'alpha-benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-9,10-dihydroergotaman
5'-benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-9,10-dihydroergotaman
9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotoman-3',6',18-trione
9,10-dihydroergotamine
dihidroergotamina
Dihydroergotamine
dihydroergotaminum

Definition

Ergotamine in which a single bond replaces the double bond between positions 9 and 10. A semisynthetic ergot alkaloid with weaker oxytocic and vasoconstrictor properties than ergotamine, it is used (as the methanesulfonic or tartaric acid salts) for the treatment of migraine and orthostatic hypotension.

References

beilstein:78887
cas:511-12-6
drugbank:DB00320
drugcentral:888
kegg.compound:C07798
kegg.drug:D07837
knapsack:C00001724
lincs.smallmolecule:LSM-3619
pubmed:10954953
pubmed:20132337
pubmed:8145914
wikipedia.en:Dihydroergotamine

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from dihydroergotamine

Phenotype where environments contain dihydroergotamine

Phenotype modified by environments containing dihydroergotamine

Phenotype affecting dihydroergotamine

Human Disease Model