seliciclib

Term ID

CHEBI:45307

Synonyms

• (2R)-2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2-yl)amino)-1-butanol
• (2R)-2-{[6-(benzylamino)-9-(1-methylethyl)-9H-purin-2-yl]amino}butan-1-ol
• (2R)-2-{[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]amino}butan-1-ol
• (R)-2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2-yl)amino)-1-butanol
• 2-(R)-(1-ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine
• CYC202
• R-ROSCOVITINE
• Roscovitine
• seliciclib

Definition

2,6-Diaminopurine carrying benzylamino, (2R)-1-hydroxybutan-2-yl and isopropyl substituents at C-6, C-2-N and N-9 respectively. It is an experimental drug candidate in the family of pharmacological cyclin-dependent kinase (CDK) inhibitors.

References

• CAS:186692-46-6
• LINCS:LSM-1001
• PDBeChem:RRC
• PMID:25148827
• PMID:25378060
• PMID:25650699
• PMID:25726754
• PMID:25747275
• PMID:25938685
• PMID:26024233
• Reaxys:7694281
• Wikipedia:Seliciclib

Ontology

ChEBI  ( EBI )