2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine

Term ID

CHEBI:44811

Synonyms

• (2R)-2-acetoxy-3-(hexadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate
• (R)-7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphapentacosan-1-aminium hydroxide inner salt 4-oxide
• 1-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine
• 1-O-hexadecyl PAF
• 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine
• 1-O-hexadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine
• 1-O-hexadecyl-2-O-acetyl-sn-glycero-3-phosophocholine
• 1-O-hexadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine
• 1-O-hexadecyl-platelet-activating factor
• C16 PAF
• C16-PAF
• C16:0 PAF
• PAF
• Platelet activating factor
• platelet-activating factor
• platelet-activating factor C16

Definition

A 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine betaine which has hexadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis.

References

• CAS:74389-68-7
• DrugBank:DB02261
• LIPID_MAPS_instance:LMGP01020046
• PDBeChem:PFS
• PMID:19075994
• PMID:19827129
• PMID:20431963
• PMID:21347278
• PMID:21804199
• PMID:22924390
• PMID:23169529
• Reaxys:3574588
• Wikipedia:Platelet-activating_factor

Ontology

ChEBI  ( EBI )