dextromethorphan

Term ID

CHEBI:4470

Synonyms

• (+)-3-methoxy-N-methylmorphinan
• (+)-dextromethorphan
• (4aS,10S,10aS)-6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene
• (9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan
• 3-methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan
• 3-methoxy-17-methylmorphinan
• Albutussin
• Antussan
• BA 2666
• BA-2666
• Balminil DM
• Benylin DM
• Calmylin
• D-methorphan
• Delsym
• destrometerfano
• dextromethorfan
• dextromethorphan
• dextromethorphane
• dextromethorphanum
• dextrometorfano
• Dextromorphan
• DXM
• Medicon
• Romilar
• Tusilan

Definition

A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene in which the sterocenters at positions 4a, 10 and 10a have S-configuration. It is a prodrug of dextrorphan and used as an antitussive drug for suppressing cough.

References

• cas:125-71-3
• drugbank:DB00514
• drugcentral:842
• hmdb:HMDB0001920
• kegg.compound:C06947
• kegg.drug:D03742
• lincs.smallmolecule:LSM-2726
• pubmed:10869398
• pubmed:12711372
• pubmed:15505150
• pubmed:17157116
• pubmed:17461892
• pubmed:17573115
• pubmed:18160193
• pubmed:18198471
• pubmed:24269965
• pubmed:2660263
• pubmed:31094746
• pubmed:7976530
• pubmed:8158182
• pubmed:9705419
• reaxys:88549
• wikipedia.en:Dextromethorphan

Ontology

ChEBI  ( EBI )

Resources

CTD