devazepide

Term ID

CHEBI:4460

Synonyms

• (S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide
• 3(S)-(-)-1,3-Dihydro-3-(2-indolecarbonylamino)-1-methyl-5-phenyl-2H-(1,4)benzodiazepin-2-one
• devazepida
• devazepide
• devazepidum
• L 364718
• MK-329
• N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide

Definition

An indolecarboxamide obtained by formal condensation of the carboxy group of indole-2-carboxylic acid with the exocyclic amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one. A cholecystokinin antagonist used for treatment of gastrointestinal disorders.

References

• cas:103420-77-5
• kegg.compound:C11710
• kegg.drug:D02693
• lincs.smallmolecule:LSM-2674
• patent:US2003139396
• patent:US2003153592
• patent:US4820834
• patent:US5153191
• patent:US5428031
• pubmed:19407653
• pubmed:23597562
• reaxys:5156082
• wikipedia.en:Devazepide

Ontology

ChEBI  ( EBI )