hydroxyurea

Term ID

CHEBI:44423

Synonyms

• carbamohydroxamic acid
• carbamohydroximic acid
• carbamoyl oxime
• carbamyl hydroxamate
• hidroxicarbamida
• hydrea
• Hydroxycarbamid
• hydroxycarbamide
• hydroxycarbamidum
• Hydroxyharnstoff
• Hydroxyurea
• N-carbamoylhydroxylamine
• N-HYDROXYUREA
• oxyurea

Definition

A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease.

References

• beilstein:1741548
• cas:127-07-1
• drugbank:DB01005
• drugcentral:1399
• gmelin:130423
• hmdb:HMDB0015140
• kegg.compound:C07044
• kegg.drug:D00341
• metacyc.compound:HYDROXY-UREA
• patent:US2705727
• pdb-ccd:NHY
• pubmed:11285159
• pubmed:11298103
• pubmed:11364534
• pubmed:11365149
• pubmed:11391710
• pubmed:12107454
• pubmed:14988684
• pubmed:15772364
• pubmed:15994344
• pubmed:16356682
• pubmed:22983419
• pubmed:23318979
• pubmed:23643402
• pubmed:23696560
• pubmed:9271088
• reaxys:1741548
• wikipedia.en:Hydroxyurea

Ontology

ChEBI  ( EBI )

Resources

CTD