meropenem

Term ID

CHEBI:43968

Synonyms

• (1R,5S,6S)-2-[(3S,5S)-5-DIMETHYLAMINOCARBONYLPYRROLIDIN-3-YLTHIO]-6-[(R)-1-HYDROXYETHYL]-1-METHYLCARBAPEN-2-EM-3-CARBOXYLIC ACID
• (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• (6S)-2-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-1beta-methyl-2,3-didehydro-1-carbapenam-3-carboxylic acid
• Antibiotic SM 7338
• MEPM
• Meropenem
• meropenem anhydrous
• meropenemum

Definition

A carbapenemcarboxylic acid in which the azetidine and pyrroline rings carry 1-hydroxymethyl and in which the azetidine and pyrroline rings carry 1-hydroxymethyl and 5-(dimethylcarbamoyl)pyrrolidin-3-ylthio substituents respectively.

References

• beilstein:6826115
• cas:96036-03-2
• drugbank:DB00760
• drugcentral:1709
• lincs.smallmolecule:LSM-5208
• patent:EP126587
• patent:US4943569
• pdb-ccd:MER
• pubmed:10776838
• pubmed:11069213
• pubmed:18611786
• pubmed:18645546
• pubmed:28343819
• pubmed:28371721
• pubmed:28583381
• pubmed:28669829
• pubmed:28677407
• pubmed:7588092
• wikipedia.en:Meropenem

Ontology

ChEBI  ( EBI )

Resources

CTD