Search Ontology:
ChEBI

deguelin

Term ID
CHEBI:4357
Synonyms
  • (-)-cis-deguelin
  • (-)-deguelin
  • (7aS,13aS)-13,13a-dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one
  • (7aS,13aS)-9,10-dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one
  • (7aS,13aS)-9,10-dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-pyrano[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-7(7aH)-one
Definition
A rotenone that is 13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one substituted by methoxy groups at positions 9 and 10, and by two methyl groups at position 3 (the 7aS,13aS-stereoisomer). It exists in abundant quantities in the bark, roots, and leaves of the Leguminosae family of plants and reported to exert anti-tumour effects in various cancers.
References
  • cas:522-17-8
  • chemspider:97058
  • hmdb:HMDB0250941
  • kegg.compound:C10417
  • knapsack:C00002522
  • lincs.smallmolecule:LSM-3368
  • lipidmaps:LMPK12060019
  • metacyc.compound:CPD-12163
  • pubmed:27771933
  • pubmed:28471807
  • pubmed:29157837
  • pubmed:30018008
  • pubmed:30078209
  • pubmed:30255595
  • pubmed:30405048
  • pubmed:30588113
  • pubmed:30741976
  • pubmed:30765727
  • pubmed:30933320
  • pubmed:31211467
  • pubmed:31504284
  • pubmed:31584382
  • pubmed:31917237
  • pubmed:32081857
  • pubmed:32128091
  • pubmed:32454059
  • pubmed:32540381
  • pubmed:33581287
  • pubmed:33724011
  • pubmed:34626304
  • pubmed:34644595
  • pubmed:9270008
  • wikipedia.en:Deguelin
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from deguelin
Phenotype where environments contain deguelin
Phenotype modified by environments containing deguelin
Phenotype affecting deguelin
Human Disease Model