dapsone

Term ID

CHEBI:4325

Synonyms

• 1,1'-sulfonylbis(4-aminobenzene)
• 4,4'-dapsone
• 4,4'-diaminodiphenyl sulfone
• 4,4'-sulfonylbisaniline
• 4,4'-Sulfonylbisbenzenamine
• 4,4'-sulfonyldianiline
• 4-(4-amino-benzenesulfonyl)-phenylamine
• 4-(4-aminophenylsulfonyl)aniline
• 4-(4-aminophenylsulfonyl)benzenamine
• 4-aminophenyl sulfone
• bis(4-aminophenyl)sulfone
• Bis(p-aminophenyl) sulfone
• DADPS
• dapsona
• DAPSONE
• dapsonum
• DDS
• DIAPHENYLSULFONE
• p,p'-diaminodiphenyl sulfone
• p,p-sulphonylbisbenzamine
• p,p-sulphonylbisbenzenamine
• p-aminophenyl sulfone

Definition

A sulfone that is diphenylsulfone in which the hydrogen atom at the 4 position of each of the phenyl groups is substituted by an amino group. It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy.

References

• CAS:80-08-0
• DrugBank:DB00250
• Drug_Central:782
• HMDB:HMDB0014395
• KEGG:C07666
• KEGG:D00592
• LINCS:LSM-5714
• PMID:16361748
• PMID:18035772
• PMID:24232126
• PMID:24512442
• PMID:28434260
• PMID:28699887
• PMID:28732451
• PMID:29045131
• PMID:29192974
• PMID:29192999
• PMID:29233746
• PMID:29280553
• Patent:FR829926
• Reaxys:788055
• Wikipedia:Dapsone

Ontology

ChEBI  ( EBI )

Resources

CTD