dapsone

Term ID

CHEBI:4325

Synonyms

1,1'-sulfonylbis(4-aminobenzene)
4,4'-dapsone
4,4'-diaminodiphenyl sulfone
4,4'-sulfonylbisaniline
4,4'-Sulfonylbisbenzenamine
4,4'-sulfonyldianiline
4-(4-amino-benzenesulfonyl)-phenylamine
4-(4-aminophenylsulfonyl)aniline
4-(4-aminophenylsulfonyl)benzenamine
4-aminophenyl sulfone
bis(4-aminophenyl)sulfone
Bis(p-aminophenyl) sulfone
DADPS
dapsona
DAPSONE
dapsonum
DDS
DIAPHENYLSULFONE
p,p'-diaminodiphenyl sulfone
p,p-sulphonylbisbenzamine
p,p-sulphonylbisbenzenamine
p-aminophenyl sulfone

Definition

A sulfone that is diphenylsulfone in which the hydrogen atom at the 4 position of each of the phenyl groups is substituted by an amino group. It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy.

References

cas:80-08-0
drugbank:DB00250
drugcentral:782
hmdb:HMDB0014395
kegg.compound:C07666
kegg.drug:D00592
lincs.smallmolecule:LSM-5714
patent:FR829926
pubmed:16361748
pubmed:18035772
pubmed:24232126
pubmed:24512442
pubmed:28434260
pubmed:28699887
pubmed:28732451
pubmed:29045131
pubmed:29192974
pubmed:29192999
pubmed:29233746
pubmed:29280553
reaxys:788055
wikipedia.en:Dapsone

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from dapsone

Phenotype where environments contain dapsone

Phenotype modified by environments containing dapsone

Phenotype affecting dapsone

Human Disease Model