Search Ontology:
ChEBI

dantrolene

Term ID
CHEBI:4317
Synonyms
  • 1-((5-(p-nitrophenyl)furfurylidene)amino)hydantoin
  • 1-({[5-(4-nitrophenyl)furan-2-yl]methylidene}amino)imidazolidine-2,4-dione
  • dantrolene
  • dantroleno
  • dantrolenum
Definition
The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
References
  • beilstein:705189
  • cas:7261-97-4
  • drugbank:DB01219
  • kegg.compound:C06939
  • kegg.drug:D02347
  • lincs.smallmolecule:LSM-3823
  • patent:NL6612588
  • patent:US3415821
  • pubmed:11934664
  • pubmed:18696266
  • pubmed:29921212
  • pubmed:30776519
  • pubmed:30948257
  • pubmed:31337666
  • pubmed:31478931
  • pubmed:31633504
  • pubmed:31775359
  • pubmed:31851793
  • pubmed:31901380
  • pubmed:31906750
  • pubmed:31918212
  • pubmed:32016838
  • pubmed:32060500
  • pubmed:8797628
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from dantrolene
Phenotype where environments contain dantrolene
Phenotype modified by environments containing dantrolene
Phenotype affecting dantrolene
Human Disease Model